Protein Info for HP15_4111 in Marinobacter adhaerens HP15

Annotation: NADH/ubiquinone/plastoquinone (complex I)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 40 to 59 (20 residues), see Phobius details amino acids 65 to 89 (25 residues), see Phobius details amino acids 103 to 119 (17 residues), see Phobius details amino acids 125 to 145 (21 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 199 to 217 (19 residues), see Phobius details amino acids 237 to 258 (22 residues), see Phobius details amino acids 264 to 284 (21 residues), see Phobius details amino acids 303 to 322 (20 residues), see Phobius details amino acids 356 to 375 (20 residues), see Phobius details amino acids 383 to 435 (53 residues), see Phobius details amino acids 442 to 462 (21 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 121 to 345 (225 residues), 134 bits, see alignment E=3.3e-43

Best Hits

Predicted SEED Role

"NADH dehydrogenase, subunit 5" in subsystem Respiratory Complex I

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PLT8 at UniProt or InterPro

Protein Sequence (524 amino acids)

>HP15_4111 NADH/ubiquinone/plastoquinone (complex I) (Marinobacter adhaerens HP15)
MFDVQAIESLFSLLVPLLFGAGAVATGLATNQSNLLARSLTFKLAFVSALAAAIGSWWWP
VDGVWFSHAPLASIMLLLITLLGMVLGRFSERYLAGDHGQRRFMIWLQVILASVAMIAIT
NHLLVFLVSWIAISVSLHQLLMFFPDRPRAALAAHKKFIFARIAELCLALAFLLLYVQYD
TPFIDRILAQVSGATEVPAGAQIAAVLMAVAALLKCAQMPFHGWLIQVVESPTPVSALLH
AGVVNLGGFLMILMAPLISEVSAAQWLLLAVAGPTAVFASLVMMTRISIKVRLAWSTCSQ
MGWMLVECALGLYELALLHLVAHSAYKAHTFLNAGNTVELSMKKRLVAVNEPGAKQWLAA
AALAGLFMLPTVFLSNEAGTAHMFSWIVPGIALTILLSEFLSAGGGVLTVARGLVIGAAF
WALYWLQKTFFGLLLAPPESQASLLEVVFVAALIAILVRGYYQIRYHRFSPAGARLYRFL
FAAGYLDEWSTRLTLKIWPAKLPDVVRPRAVVSVSSTSGSRESA