Protein Info for PGA1_c04180 in Phaeobacter inhibens DSM 17395

Annotation: phosphonates import ATP-binding protein PhnC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 TIGR02315: phosphonate ABC transporter, ATP-binding protein" amino acids 1 to 242 (242 residues), 319.3 bits, see alignment E=7.5e-100 PF00005: ABC_tran" amino acids 19 to 173 (155 residues), 113.7 bits, see alignment E=5.6e-37

Best Hits

Swiss-Prot: 90% identical to PHNC_RUEPO: Phosphonates import ATP-binding protein PhnC (phnC) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)

KEGG orthology group: K02041, phosphonate transport system ATP-binding protein (inferred from 91% identity to sit:TM1040_3709)

Predicted SEED Role

"Phosphonate ABC transporter ATP-binding protein (TC 3.A.1.9.1)" in subsystem ABC transporter alkylphosphonate (TC 3.A.1.9.1) (TC 3.A.1.9.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ETV6 at UniProt or InterPro

Protein Sequence (272 amino acids)

>PGA1_c04180 phosphonates import ATP-binding protein PhnC (Phaeobacter inhibens DSM 17395)
MLRIDKLTKRFGDKIAVDTATLDIDKPCMIGIIGRSGAGKSTLLRMINRLGDASDGRILF
EGRDVTQLRGKEKRAWQSDCAMIFQQFNLVPRMDVVSNVLHGTLNRRSTLATLFNLYPMD
DIHRAIDILDRLGIAEHAAKRAEALSGGQQQRVAIARALMQDPAIILADEPIASLDPMNA
QTVMEALRRIHEEDGRTVIANLHTLDTARRYCDRVVGMRDGRIVFDGLPEQLTTGVAREI
YGAGDDFSEAATSTEIETLNRTKPRRQPAVAV