Protein Info for Psest_4107 in Pseudomonas stutzeri RCH2

Annotation: formate dehydrogenase accessory protein FdhE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 TIGR01562: formate dehydrogenase accessory protein FdhE" amino acids 4 to 301 (298 residues), 342 bits, see alignment E=2e-106 PF04216: FdhE" amino acids 17 to 299 (283 residues), 322.9 bits, see alignment E=1.4e-100

Best Hits

Swiss-Prot: 85% identical to FDHE_PSEU5: Protein FdhE homolog (fdhE) from Pseudomonas stutzeri (strain A1501)

KEGG orthology group: K02380, FdhE protein (inferred from 85% identity to psa:PST_0163)

Predicted SEED Role

"formate dehydrogenase formation protein FdhE" in subsystem Formate hydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GS08 at UniProt or InterPro

Protein Sequence (305 amino acids)

>Psest_4107 formate dehydrogenase accessory protein FdhE (Pseudomonas stutzeri RCH2)
MAGTILEPGQIEAAASKPPFTNLPPRDLFALRSERFSKLAEGHPFADYLRLLAAVCQAQQ
QVLDNPPAMPPLDEHRTRESLKHNLPPLAADTLVRDDAWLTMLDAWLDAFVAPENPAVVA
AIRQLRDAENGQRKAWAVALVSGQYDSLPPALVPFLGAALQLAWSHQLLQLDLSDLRERE
DQTHCPCCGAPPMAGIIRHRGQLNGLRYLVCSLCACEWHYVRVKCSQCRSTKKLDYLHFE
GSPQGVKAEVCPECNSYLKQLYLDLAPDGESLSADLATLDLDMLLAEQGFQRHAPNLLLA
PGDDA