Protein Info for HP15_3973 in Marinobacter adhaerens HP15

Annotation: long-chain-fatty-acid-CoA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 696 transmembrane" amino acids 28 to 51 (24 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details PF00501: AMP-binding" amino acids 3 to 300 (298 residues), 147.5 bits, see alignment E=5e-47 PF14518: Haem_oxygenas_2" amino acids 508 to 675 (168 residues), 113.3 bits, see alignment E=1.2e-36

Best Hits

KEGG orthology group: None (inferred from 79% identity to maq:Maqu_0291)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKR5 at UniProt or InterPro

Protein Sequence (696 amino acids)

>HP15_3973 long-chain-fatty-acid-CoA ligase (Marinobacter adhaerens HP15)
MMQAAEALADQLTRLGVRRAGLCGDSSVAWILADLACLLAGVVCVPVPVFFSRTQTEHLT
ERAGLDCLLSGGASNGGEHIGHGVWLRHLPVTAAAAWMPEQTAKITFTSGSTGNPKGVCL
SVAQMTATTLALKERLEGVDLERHLCILPLATLLENIAGVYLPLLMGSTVMVAPLQDLGM
TGSSGLDIGRLVQGINEHQPQSLILVPELAMALVSAAEQKHLDSNSFRFLAVGGGRVSSD
LLARGRAVGLPLYEGYGLSECSSVVALNVPGTEREGAVGKPLSHVRVRVDDRGHILVAGN
THLGYLGDEPAGGEWLDTGDLGSRDAGGFLSVSGRAKNLLITSFGRNISPEWLESELIQA
IGARQAVVFGDGDPRPSALVVVQDGRSPEALRSQLDALNNNLPDYARLSGVYIRRQPLSQ
AEGYLTANGRPVRQQIQADLPTLLAGAFPIFMNLSISNSELSNPPGGSFMAFFDRLQSET
AQARAHVTGAPVIEAIREGRFDLNGYTWFLTQAYHHVKHTVPLMMACGGRLPERLEFVRK
ALVEYIEEEYGHHEWILNDLAACGEDKEAIRHGSPDTSIELMVAYLYDRINRGNPAAFFG
MVQVLEGTSIELATPLGEAIQKQLGLPKEAFSYLYSHGALDQEHFEFFRNLMNEITDPDD
QQAIIEAARMVYRLYGDMLHSIPVPENRKERRHEAA