Protein Info for Psest_4084 in Pseudomonas stutzeri RCH2

Annotation: oxaloacetate decarboxylase alpha subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 PF00682: HMGL-like" amino acids 7 to 269 (263 residues), 71.7 bits, see alignment E=1.7e-23 TIGR01108: oxaloacetate decarboxylase alpha subunit" amino acids 9 to 597 (589 residues), 861 bits, see alignment E=2e-263 PF02436: PYC_OADA" amino acids 294 to 482 (189 residues), 199 bits, see alignment E=1.8e-62 PF00364: Biotin_lipoyl" amino acids 535 to 600 (66 residues), 63.8 bits, see alignment E=2.7e-21 PF13533: Biotin_lipoyl_2" amino acids 571 to 601 (31 residues), 30.3 bits, see alignment (E = 6.8e-11)

Best Hits

Swiss-Prot: 54% identical to DCOA_KLEPN: Oxaloacetate decarboxylase alpha chain (oadA) from Klebsiella pneumoniae

KEGG orthology group: K01960, pyruvate carboxylase subunit B [EC: 6.4.1.1] (inferred from 94% identity to psa:PST_0187)

Predicted SEED Role

"Pyruvate carboxylase subunit B (biotin-containing) (EC 6.4.1.1)" (EC 6.4.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.4.1.1

Use Curated BLAST to search for 6.4.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GTD8 at UniProt or InterPro

Protein Sequence (602 amino acids)

>Psest_4084 oxaloacetate decarboxylase alpha subunit (Pseudomonas stutzeri RCH2)
MTAQKKITVTDTILRDAHQSLLATRMRTEDMLPICDKLDRVGYWSLEVWGGATFDACVRF
LKEDPWERLRQLKAALPNTRLQMLLRGQNLLGYRHYSDDVVEAFVAKAAANGIDVFRIFD
AMNDVRNLETAIRAVKKSGKHAQGTIAYTTSPVHTVELFVEQARAMRDMGVDSIAIKDMA
GLLTPFATGDLVRALKAEIDLPVFIHSHDTAGVASMCQLKAIESGADHIDTAISSMAWGT
SHPGTESMVAALRGTPYDTGLDLELLQEIGLYFYAVRKKYHQFESEFTGVDTRVQVNQVP
GGMISNLANQLKEQGALHRMDEVLAEIPKVRKDLGYPPLVTPTSQIVGTQAFFNVLAGER
YKTITTEVKYYLQGRYGKAPAAVSEHLRFQAIGSEEVIECRPADLIAPELDKLRNEVGAL
AKNEEDVLTYAMFPDIGRKFLEEREAGTLQPEVLLPIPGTAAAPAQGGVPTEFVIDVHGE
TYRVDITGVGVKAEGKRHFYLSIDGMPEEVVFEPLNAFVGGGGSQRKQASAPGDVSTTMP
GNVVDVLVAVGDQVKAGQTVLVSEAMKMETEIQAPIAGTVKAIHVAKGDRVNPGEVLIEI
EA