Protein Info for HP15_3895 in Marinobacter adhaerens HP15

Annotation: conserved hypothetical protein, membrane

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 355 transmembrane" amino acids 166 to 187 (22 residues), see Phobius details amino acids 207 to 230 (24 residues), see Phobius details amino acids 236 to 259 (24 residues), see Phobius details amino acids 267 to 287 (21 residues), see Phobius details amino acids 290 to 322 (33 residues), see Phobius details amino acids 331 to 349 (19 residues), see Phobius details PF13795: HupE_UreJ_2" amino acids 161 to 323 (163 residues), 139.2 bits, see alignment E=4.8e-45

Best Hits

Predicted SEED Role

"putative transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJU9 at UniProt or InterPro

Protein Sequence (355 amino acids)

>HP15_3895 conserved hypothetical protein, membrane (Marinobacter adhaerens HP15)
MTAAHKASDSFLYLDSGPTELRMDVALRDLALLMSIDSNGDNEVSGRELRQSRPEITRTV
ESALTFSNSSGNCNLAGKKWGISEHSDGVYSAARYAIRCPDGEPPEALEYNLLFKQDALH
RGLVSLDYNGQTRLAVLGPDSRTLDLAGTDTPGYFSVFKTFVYEGIVHLLIGLDHMLFLL
VLIIPATLSTAKTQGPSDQSTGLRGRLLGLAGIITAFTVAHSITLALAALDIVSLPIAWV
ETVIALSIGLAALNVAWPIFGRKTWKLAFGFGLVHGFGFASVLGDLTSGISGLAVALAGF
NLGVELGQLALLVVGFPVLVYLGKNRMYQKGAVPVMLAGIGAISLFWVVQRAPLF