Protein Info for HP15_3881 in Marinobacter adhaerens HP15

Annotation: response regulator receiver and ANTAR domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 PF08376: NIT" amino acids 46 to 285 (240 residues), 182.2 bits, see alignment E=2.2e-57 PF03861: ANTAR" amino acids 374 to 425 (52 residues), 59.4 bits, see alignment 2.4e-20

Best Hits

KEGG orthology group: None (inferred from 64% identity to maq:Maqu_0174)

Predicted SEED Role

"Response regulator NasT" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJT5 at UniProt or InterPro

Protein Sequence (432 amino acids)

>HP15_3881 response regulator receiver and ANTAR domain protein (Marinobacter adhaerens HP15)
MMNTKRNTVPEIPGAGDYLIASKTCELMSLQYFLQMGRLVQCISSLVHGLQRERGASNVF
LGSSGKKFQEERKSLAVESDRLKREFELALAEIHEELTGHPVSSRLLNQIASALHGLEGL
GELRRCVVARKVTAESATEDYSSLIHNLIAVVFEAADTAVDPTIAGLLVAMVHLMNGKEL
CGQERAVGSAGFSSGAFDRALSERMAHLIEAQERCFEVFAGFADADSLSLWQKVSSHERE
GEIERMRRLASSVGRFKDLDPELADQWFKLMTERIDALKQIEDSVEGCFHTRCIERFAAA
KKSLAHQETLVASLDTGGAASQPLLVLCNSGSEGSTGEAFSSEGMGQQFGRSIFELVQEQ
TRSLQKMTDELQSAKEALEDRKTQEKAVLLLMKHRKISNDEAHRLLRKLAMDQGRKLPEV
ARSLISMADVLK