Protein Info for HP15_3857 in Marinobacter adhaerens HP15

Annotation: RNA polymerase, sigma 70 subunit, RpoD family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 96 to 322 (227 residues), 120.1 bits, see alignment E=3.8e-39 PF04542: Sigma70_r2" amino acids 100 to 167 (68 residues), 72.4 bits, see alignment E=3.2e-24 PF04539: Sigma70_r3" amino acids 180 to 253 (74 residues), 42.9 bits, see alignment E=6.4e-15 PF04545: Sigma70_r4" amino acids 269 to 320 (52 residues), 57.6 bits, see alignment 1.1e-19

Best Hits

KEGG orthology group: None (inferred from 76% identity to maq:Maqu_0150)

Predicted SEED Role

"RNA polymerase sigma factor RpoS" in subsystem Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJ23 at UniProt or InterPro

Protein Sequence (332 amino acids)

>HP15_3857 RNA polymerase, sigma 70 subunit, RpoD family (Marinobacter adhaerens HP15)
MRTTERLGPSPTTPNDGERDSLVGLYFRDASRYELLTDEAERRLSRKLTLCYRIISTELA
LPEETPQTFREVIGSLGDACAFSSRCRRAFHLATACRRKLIQSNLRLAVHIARRYGQHGI
PMSDLIQDANVGLIKAVERFDPTKGFRFSTYAYWWISEEVKRCLQRGTRLVHTPENVVDE
IRQLHKVSLRMHQSLGRTPSQSELAREMEASPSRIGELRALATREISTDVPLVEDGSVTL
GDSLDAGDQMAPDHPMSDRDRQRTLKSMLSELNDREKDILSRRYGLGLPEPETLQVISDD
LGISRERVRQIEKTALKKLQSRYESPEDAFGA