Protein Info for HP15_3855 in Marinobacter adhaerens HP15
Annotation: 2,4-diaminobutyrate 4-transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 58% identical to ECTB_VIBPA: Diaminobutyrate--2-oxoglutarate transaminase (ectB) from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
KEGG orthology group: K00836, diaminobutyrate-2-oxoglutarate transaminase [EC: 2.6.1.76] (inferred from 92% identity to maq:Maqu_0148)Predicted SEED Role
"Diaminobutyrate-pyruvate aminotransferase (EC 2.6.1.46)" in subsystem Ectoine biosynthesis and regulation (EC 2.6.1.46)
MetaCyc Pathways
- ectoine biosynthesis (5/5 steps found)
- norspermidine biosynthesis (3/6 steps found)
- ectoine degradation (1/4 steps found)
- superpathway of polyamine biosynthesis III (3/8 steps found)
- rhizobactin 1021 biosynthesis (1/7 steps found)
- pyoverdine I biosynthesis (2/11 steps found)
- baumannoferrin biosynthesis (1/11 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.6.1.46 or 2.6.1.76
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E4PJ21 at UniProt or InterPro
Protein Sequence (422 amino acids)
>HP15_3855 2,4-diaminobutyrate 4-transaminase (Marinobacter adhaerens HP15) MEIFKSTESEVRVYSRAFPVIFNRAKNAHLYTEDGKEYLDFLAGAGSLNYGHNNDTLKKA LLEYIEADGVSQGLDMFTTAKHDFMESYKKHILDPRGLDYKMQFTGPTGTNCVEAALKLA RKVKGRSGIISFTNGFHGVTMGAVATTGNKHHRGGVGTPLGNVDFMFYDGYLGDDVDTLA IMDKLLSDGSSGFELPAAVIVEAVQGEGGLNACRAEWLKGLSELCKKHDILLILDDIQAG NGRTGEFFSFEFAGIKPDIVTVSKSLSGYGLPMALVLFKPELDVWDPGEHNGTFRGNNMA FITARAAVENYWKDDAFANEVKAKTEVLGDALQSICDKYPGQFKMKGRGLMRGIEAKHAD ITGPITKRAFEHGLIIETSGPNDEVIKCLMPLTTSEEDLKKGAALLAKSVDEIMQEGLSE AS