Protein Info for Psest_3976 in Pseudomonas stutzeri RCH2

Annotation: PAS domain S-box

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 648 PF00072: Response_reg" amino acids 8 to 117 (110 residues), 66.8 bits, see alignment E=3.7e-22 amino acids 531 to 642 (112 residues), 63.3 bits, see alignment E=4.6e-21 TIGR00229: PAS domain S-box protein" amino acids 131 to 247 (117 residues), 25.2 bits, see alignment E=7.6e-10 PF08448: PAS_4" amino acids 143 to 242 (100 residues), 29.8 bits, see alignment E=1.2e-10 PF00512: HisKA" amino acids 282 to 347 (66 residues), 30.2 bits, see alignment E=7.6e-11 PF02518: HATPase_c" amino acids 391 to 507 (117 residues), 61 bits, see alignment E=2.9e-20

Best Hits

KEGG orthology group: None (inferred from 88% identity to psa:PST_0304)

Predicted SEED Role

"Histidine kinase/response regulator hybrid protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GSU6 at UniProt or InterPro

Protein Sequence (648 amino acids)

>Psest_3976 PAS domain S-box (Pseudomonas stutzeri RCH2)
MERDSRLLIVDDNATTRYAMRRVLERHGYQVLEAGTGSEGLALVAGADALILDVNLPDMS
GFDIARQLRADPNTALLPLIHVSAASIETNDIITGLDAGGDAYLIHPVDPDVLLATLRTL
LRVRDTERALRDSEARFREIFIHVAAPIAVLDADLGLHECNHAFELLIGAASPAAALLSE
VFAPGQEALVAELRAHLQAGERWRTPLQMRVNGETRETEWQISPYRTPGLGLVFVEDVTE
QRHRERAQRQEIANTTSKLAHEVAERARTEEQLLQAQKMDALGKLTGGIAHDFNNLLTGI
ITGIELMKQRIIEGRADSVLRFADASLSSARSAASLTNRLLAFARKQPLDARALNINERI
RSLEDLLRRTIGERITLTFDFTDEPAVARVDVSQFESALLNLVINARDALPEGGHIRIST
FLSDGSQTQELAAGRYIGLCVGDDGTGIEPGVLDKVFDPFFTTKPQGRGTGLGLSSIYGF
ALQSGGDASIRSTLGVGTEVTLLLPAASGEAIVASPIGADSSARLAGHEHVLVVEDMPSV
RMLVAETLIEAGYRCSQAGDVETAQALLEADTSIELLLTDVGLPRLSGRQLAQWARRARP
GLPVILITGYAENAASREGFIDERMDLVLKPFEAADLLSKIRGLLDEA