Protein Info for Psest_3975 in Pseudomonas stutzeri RCH2

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 PF00512: HisKA" amino acids 57 to 124 (68 residues), 63.4 bits, see alignment E=1.6e-21 PF02518: HATPase_c" amino acids 171 to 281 (111 residues), 98.9 bits, see alignment E=2.5e-32

Best Hits

KEGG orthology group: None (inferred from 91% identity to psa:PST_0305)

Predicted SEED Role

"Putative SigmaB asociated two-component system sensor protein" in subsystem SigmaB stress responce regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GT20 at UniProt or InterPro

Protein Sequence (290 amino acids)

>Psest_3975 Signal transduction histidine kinase (Pseudomonas stutzeri RCH2)
MADPMLPETGDAARIELLRQENELLRAELEETNQGVLALYAELDTQADQLRQASELKSRF
LSYMSHEFRTPLGSILSITRLLSDELDGPLSPEQHKQVRFVSSAASELSEMVDDLLDLAK
IEAGRVSISPAWFDMLDLFSALRGMFRPIVEGSPVDLIFEEPVGLPRFYTDDKKLAQILR
NFISNALKFTPQGEVRVSARMENPQQVRFAVSDTGIGIAAELHDRLFEDFAQVDSPLQKR
LRGTGLGLALCKRFAELLGGRVGVESTPGKGSEFYVIIPFAIQAEEPDGA