Protein Info for Psest_3964 in Pseudomonas stutzeri RCH2

Annotation: formate dehydrogenase family accessory protein FdhD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00129: formate dehydrogenase family accessory protein FdhD
  • amino acids 39 to 265 (227 residues), 158 bits, E=1.4e-50
• PF02634: FdhD-NarQ
  • amino acids 41 to 274 (234 residues), 214.6 bits, E=9.4e-68

Best Hits

Swiss-Prot: 40% identical to FDHD_ACIAD: Sulfur carrier protein FdhD (fdhD) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K02379, FdhD protein (inferred from 72% identity to psp:PSPPH_0140)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

See L0GNU7 at UniProt or InterPro

Protein Sequence (282 amino acids)

>Psest_3964 formate dehydrogenase family accessory protein FdhD (Pseudomonas stutzeri RCH2)
MNAPSRLTAAFAGAVQSPAGASQRYCYQPIDEPEQRSVDLAEECALAIAYNGLSQAVMMI
SPADLEDFVVGFSLANGFVDSLDDIYDIRVHGCGSARRAEVDIASRAFWRLKQQRRQLPG
NSSCGLCGVEALEQALPRLPALAPSALPPSHWLQDLRQRIGEFQPLGRDCGAVHAALFMD
ANGEIRLGREDIGRHNALDKLIGALARANQAAEGGLAIVTSRCSLELVHKVQRAGIPTLV
SLSSPTGLAAKWAQRHNLNLIHLPHHSPPRVYSPAVPTLNAR