Protein Info for HP15_3822 in Marinobacter adhaerens HP15

Annotation: drug resistance transporter, EmrB/QacA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 19 to 42 (24 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 112 to 134 (23 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 207 to 226 (20 residues), see Phobius details amino acids 238 to 255 (18 residues), see Phobius details amino acids 275 to 299 (25 residues), see Phobius details amino acids 311 to 329 (19 residues), see Phobius details amino acids 341 to 358 (18 residues), see Phobius details amino acids 364 to 387 (24 residues), see Phobius details amino acids 408 to 427 (20 residues), see Phobius details amino acids 440 to 459 (20 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 22 to 425 (404 residues), 284.7 bits, see alignment E=6.9e-89 PF07690: MFS_1" amino acids 25 to 417 (393 residues), 186.9 bits, see alignment E=2.5e-59

Best Hits

KEGG orthology group: None (inferred from 78% identity to maq:Maqu_0114)

Predicted SEED Role

"FIG00783923: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIY8 at UniProt or InterPro

Protein Sequence (463 amino acids)

>HP15_3822 drug resistance transporter, EmrB/QacA family (Marinobacter adhaerens HP15)
MADNSVEGLKARYGDRWRWLAVATVMIGTMATVLSATVVNVALHDIMVEFGIRQGQVHWL
ATGFIAAMTTTMLASSWLLDHFGVRKTLAVAMFLFTLISLAGGFAETPGQLIAARIGQGA
MAGLMQPMGMYLVFRIFPRDRRGQAMGIYGMGVILAPALGPVLGGFLVDQLDWRYVMFAP
APVTLLGVFMAWRFLPLPVSRPAPYRFDLPGLVLLGFTIALSLDALNRLQQAAGQKSWIL
IEGLLALGGLLLFVLRERQTAHPLVNIALLRKPVFVFACLGAMALGLALFGSTYLIPLFV
QTALGFSATEAGLLMLPAGIVLGMTFPLAGRMADRHSARGLVVFGIGAFALSAVLFALSD
LELAFGWLVLWTVLGRIGIGFMLPALSTGALNPLEPQELGAGSSTLNFMRQLGGAFGVNL
VALTIEFGEHTSGMPTINAFHSAWWLVAAFVAVAAIPVWRMRV