Protein Info for HP15_3804 in Marinobacter adhaerens HP15

Annotation: esterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 PF00144: Beta-lactamase" amino acids 51 to 390 (340 residues), 175.3 bits, see alignment E=9.9e-56

Best Hits

KEGG orthology group: None (inferred from 83% identity to maq:Maqu_0097)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIX0 at UniProt or InterPro

Protein Sequence (428 amino acids)

>HP15_3804 esterase (Marinobacter adhaerens HP15)
MNRLARRALHSSQIPEDLESVTFRDDAGENPAAAGVSQETVDALWRSVQSLYRTGVHPGI
QISIRHKGEQVLHRAIGHASGNGPHDPRDAAKVPMTTDTPICYFSASKAVTALLMHMLAE
QGLVNLMDPVSYYCPEFGVNGKRTITVHQILSHRGGIPAIPRETPIDVLWDNDEIWRLLC
AARPVEVDGAKVAYHAITGGFVLQRVLERVTGDSIEKYLDKHLRRPMGMKWFTYGIAPEH
LDELACNYATGPTPRFPVSWVVNRALGGDIRTVERVTNDPRFQEAVIPAGNLCGTAEEMG
RFFQMMLNGGLWNGRRICSEITIRRAIQQFGSLQIDRTMMIPMRFSAGMMLGGNPVGLWG
QNSRFAFGHVGLINKLCWADAARDISVSLLNTGIPIVGHHLPALAKFVYTVGNRFPLIPE
HRRPLIAA