Protein Info for Psest_3926 in Pseudomonas stutzeri RCH2

Annotation: GTP-binding protein TypA/BipA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 606 PF00009: GTP_EFTU" amino acids 4 to 196 (193 residues), 197.4 bits, see alignment E=4.4e-62 TIGR00231: small GTP-binding protein domain" amino acids 5 to 134 (130 residues), 82.7 bits, see alignment E=2.6e-27 TIGR01394: GTP-binding protein TypA/BipA" amino acids 5 to 600 (596 residues), 940.9 bits, see alignment E=2.4e-287 PF01926: MMR_HSR1" amino acids 8 to 129 (122 residues), 27.5 bits, see alignment E=7.4e-10 PF03144: GTP_EFTU_D2" amino acids 219 to 289 (71 residues), 39.1 bits, see alignment E=2.1e-13 PF00679: EFG_C" amino acids 398 to 477 (80 residues), 76 bits, see alignment E=4.8e-25 PF21018: BipA_C" amino acids 486 to 594 (109 residues), 150.9 bits, see alignment E=2.5e-48

Best Hits

Swiss-Prot: 72% identical to TYPA_ECO57: GTP-binding protein TypA/BipA (typA) from Escherichia coli O157:H7

KEGG orthology group: K06207, GTP-binding protein (inferred from 97% identity to psa:PST_0355)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GSP2 at UniProt or InterPro

Protein Sequence (606 amino acids)

>Psest_3926 GTP-binding protein TypA/BipA (Pseudomonas stutzeri RCH2)
MIENLRNIAIIAHVDHGKTTLVDKLLRLSGTLDRKELENERVMDSNDQEKERGITILAKN
TALKWNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQDGPMPQTRFVTQKAFKAG
LRPIVVVNKIDRPGARPDWVIDQIFDLFDNLGATDEQLDFPIVYASALNGIAGMDHEKMD
DNMDALFQAIIDHVPSPKVDLDGPFQMQISQLDYNSFLGVIGIGRIARGTIKANSPVTAI
GADGKKRNGRILKIMGHSGLQRVEVQEAEAGDIVCVSGMDELYISDTLCDQNNVEALPPL
TVDQPTVSMTFQVNDSPFAGKEGKFVTSRNIKDRLEKELLHNVALRVEPGDSPEKFKVSG
RGELHLSVLIETMRREGFELAVGRPEVVIIENEAGEKQEPYENVTIDIEEQHQGPVMEQM
GLRKGDLSNMVPDGKGRVRLEYTIPARGLIGFRNNFLTLTSGSGILTSTFSHYGAIKAGE
VTNRQNGVLVSMATGTALTYSLETLQARGKLFLAPGDEIYEGQLCGINSRDNDLVLNPTK
GKKLDNMRASGKDEVIALVPPIKFTLEQALEFIADDELVEVTPKSIRLRKKYLNENDRKR
FERSKV