Protein Info for PGA1_78p00130 in Phaeobacter inhibens DSM 17395

Annotation: putative oxidoreductase, GFO/IDH/MOCA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF01408: GFO_IDH_MocA" amino acids 10 to 138 (129 residues), 78.4 bits, see alignment E=1.2e-25 PF22725: GFO_IDH_MocA_C3" amino acids 148 to 278 (131 residues), 112.4 bits, see alignment E=2.2e-36 PF02894: GFO_IDH_MocA_C" amino acids 151 to 371 (221 residues), 79.6 bits, see alignment E=4.7e-26

Best Hits

Swiss-Prot: 41% identical to Y4HM_SINFN: Uncharacterized oxidoreductase y4hM (NGR_a03370) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 65% identity to bra:BRADO0445)

Predicted SEED Role

"Oxidoreductase, Gfo/Idh/MocA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E6Q0 at UniProt or InterPro

Protein Sequence (374 amino acids)

>PGA1_78p00130 putative oxidoreductase, GFO/IDH/MOCA family (Phaeobacter inhibens DSM 17395)
MTTDHKTRLKLGMVGGGQGAFIGAVHRIAARMDDRFQLVAGALSSDPARASASAAELGID
PDRSYASFAEMAEAEAAREDGIDAVAIVTPNHLHAGPSIAFLNAGIHVICDKPLAASVAE
AEAIKDAARSSSARFFLTHNYTGYPLLRQARAMVARGDLGRIRLVQAEYAQDWLTNVIEQ
EGHKQAAWRTDPAQSGAGAIGDIGTHAFNIACFVSGLAPQALSAELHSFGPGRQVDDNAH
ILLRYAEGARGMLWASQIAVGCENSLRLRIYGDKGGLEWEHQDPNQMTFTRFGEPKQILT
RGGANIGPDWTRVPPGHPEGYLEGFATLYTDIAEVIETGTDNPMLPGLQAGLDGMWFISA
AQTSSAEGGAWIPR