Protein Info for Psest_3912 in Pseudomonas stutzeri RCH2

Annotation: His Kinase A (phosphoacceptor) domain./HAMP domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 transmembrane" amino acids 17 to 40 (24 residues), see Phobius details amino acids 173 to 193 (21 residues), see Phobius details PF00672: HAMP" amino acids 202 to 243 (42 residues), 30.4 bits, see alignment 6.1e-11 PF00512: HisKA" amino acids 274 to 335 (62 residues), 43.6 bits, see alignment E=3.8e-15 PF02518: HATPase_c" amino acids 381 to 485 (105 residues), 69.4 bits, see alignment E=5.3e-23

Best Hits

KEGG orthology group: None (inferred from 92% identity to psa:PST_0363)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GRG7 at UniProt or InterPro

Protein Sequence (493 amino acids)

>Psest_3912 His Kinase A (phosphoacceptor) domain./HAMP domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (Pseudomonas stutzeri RCH2)
MTHVSIWQRPSSLRGALLLKVVVPLMAIMFGFSSVVLWTVERNSERRLQAEVELVARAVR
LPLSASLEKNHERTLQQVLESVLGVGRVYGAYVYDRDGKLAAYAGAAEPDQDESAIQQLT
AGGELTGTYQRINGRPVYSYFVPLEESGGQINGLLQVTRRWGDFEQDIRRLRLIAAGLGG
LLAGVALVVILLGHRSAVGKHLQQLARSMERVAAGEREHRAPRSGPQEIVVLSGALNQML
DSIAAAERQVAEQQTREEQLQARLRQSQQLAAVGRLAAGVAHELGSPLSVIDGKAQRVLR
DDELGETHRRALLQIRQQVARLSAIVRQLLDFGRAAGSPPRSVPAEVLAHSAAAAVADEL
AALQVRLELLAPAQTVYCRVDPPRFEQALTNLLRNAAQASPGGLVRLSWWQDGNELLLQV
EDDGPGVAEANRAALFEPFFTTKAVGEGSGLGLAVAHGVVSECGGRLELVDGSLPGAAFR
IALPLIDEEVGHD