Protein Info for HP15_3761 in Marinobacter adhaerens HP15

Annotation: transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 54 to 74 (21 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 119 to 138 (20 residues), see Phobius details amino acids 147 to 171 (25 residues), see Phobius details amino acids 192 to 214 (23 residues), see Phobius details amino acids 235 to 255 (21 residues), see Phobius details amino acids 260 to 279 (20 residues), see Phobius details amino acids 291 to 310 (20 residues), see Phobius details amino acids 332 to 353 (22 residues), see Phobius details amino acids 360 to 387 (28 residues), see Phobius details amino acids 422 to 439 (18 residues), see Phobius details PF13726: Na_H_antiport_2" amino acids 2 to 85 (84 residues), 102 bits, see alignment E=3.2e-33 PF02447: GntP_permease" amino acids 4 to 246 (243 residues), 24.2 bits, see alignment E=2.7e-09 PF03553: Na_H_antiporter" amino acids 150 to 434 (285 residues), 267.2 bits, see alignment E=4e-83 PF06808: DctM" amino acids 188 to 390 (203 residues), 32.2 bits, see alignment E=1.1e-11

Best Hits

Swiss-Prot: 60% identical to Y2115_VIBPA: Uncharacterized membrane protein VP2115 (VP2115) from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

KEGG orthology group: K07084, (no description) (inferred from 89% identity to maq:Maqu_0056)

Predicted SEED Role

"Histidine permease YuiF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PI39 at UniProt or InterPro

Protein Sequence (440 amino acids)

>HP15_3761 transport protein (Marinobacter adhaerens HP15)
MNAVVAAVAIMLVLSLCRIHVVVALIIGAVSGGLIAGMSLEATIEAFNSGLGGGATVALS
YATLGAFAVAIGKSGLAHALADRALALVGRQEEGAAVNGIRFLIIGLLLAIAISSQNILP
IHIAFIPLVVPPLLYVMAKLSMDRRLVACVLTFGLITPYMFLPVGFGGIYLNEILIAKIN
ANGVDASGLSVMKAMALPALGMLCGLLIAVFFSYRRGRTYNLETITKAERVDTSYSPRTL
VMALLAIVTAFVVQLWLGSMILGALAGFVLFNLSGVVRWKEADDLFTEGMKMLAMIGFIM
IAASGFAEVMRETGEIASLVDSSVGVIGENKAMAALLMLVVGLLITMGIGSSFSTIPIIA
ALYVPLALQLGFSPLAIVALVGTAGALGDAGSPASDSTLGPTAGLNADGQHNHIWDTVVP
TFLHYNLPLLGFGWLAAMVL