Protein Info for HP15_3741 in Marinobacter adhaerens HP15

Annotation: potassium transporter peripheral membrane component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF13241: NAD_binding_7" amino acids 2 to 87 (86 residues), 23.1 bits, see alignment E=5.9e-08 PF03807: F420_oxidored" amino acids 2 to 50 (49 residues), 22 bits, see alignment 1.4e-07 PF02558: ApbA" amino acids 3 to 92 (90 residues), 24.8 bits, see alignment E=9.6e-09 PF02254: TrkA_N" amino acids 3 to 106 (104 residues), 90.7 bits, see alignment E=5.4e-29 amino acids 244 to 359 (116 residues), 91.7 bits, see alignment E=2.7e-29 PF03435: Sacchrp_dh_NADP" amino acids 3 to 107 (105 residues), 26 bits, see alignment E=6.6e-09 PF02080: TrkA_C" amino acids 164 to 234 (71 residues), 45.1 bits, see alignment E=4.8e-15 amino acids 400 to 460 (61 residues), 37.8 bits, see alignment E=9e-13

Best Hits

Swiss-Prot: 52% identical to TRKA_HAEIN: Trk system potassium uptake protein TrkA (trkA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03499, trk system potassium uptake protein TrkA (inferred from 92% identity to maq:Maqu_0040)

Predicted SEED Role

"Trk system potassium uptake protein TrkA" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PI19 at UniProt or InterPro

Protein Sequence (467 amino acids)

>HP15_3741 potassium transporter peripheral membrane component (Marinobacter adhaerens HP15)
MKILILGAGQVGGTLAENLANEANDITIIDSDGARLRELQDRLDIRTVQGAASYPTALRQ
AGAEDADMLIAVTNSDETNMVACQVAKLLYKTPTTICRVRANAYLAKSELFYQRDQTKDL
DSLRGFPIDVLISPEHLVTKHITRLIENPGALQVLEFSKGLTRLVAIRATKGGPLVGHEL
SYLRTHMPKIDTRVAAIFRKDRAIMPEGNTVIEDGDEVFFIAAGDHIKSVMSELQPLVKP
YKRIFICGGGNIGQRLAHTLENRYQVKLLERDHERCVMLSENLRKTVVLEGNAANKDILL
EENIESTDVFCAVTNDDEANIMASLLAKRLGARKVLTLINNPDYVDLIQGGDIDVAISPQ
QTTIGSLLTHVRRGDVVNVHSLRRGAAEAIEAIAHGDHRSSKVVGKRLDEINLPEGTTIG
AIVRRNEVLIAHDHLRIQPDDHVILFLVDKTRIRDVEKLFQVGLTFF