Protein Info for Psest_3842 in Pseudomonas stutzeri RCH2

Annotation: Transcriptional regulators

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 PF00392: GntR" amino acids 14 to 75 (62 residues), 55.6 bits, see alignment E=3.3e-19 PF07729: FCD" amino acids 100 to 230 (131 residues), 88.3 bits, see alignment E=5.5e-29

Best Hits

Swiss-Prot: 69% identical to GLCC_ECOLI: Glc operon transcriptional activator (glcC) from Escherichia coli (strain K12)

KEGG orthology group: K11474, GntR family transcriptional regulator, glc operon transcriptional activator (inferred from 98% identity to psa:PST_0430)

Predicted SEED Role

"Glycolate utilization operon transcriptional activator GlcC" in subsystem Glycolate, glyoxylate interconversions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GR94 at UniProt or InterPro

Protein Sequence (257 amino acids)

>Psest_3842 Transcriptional regulators (Pseudomonas stutzeri RCH2)
MQNEKHNDRRQVADVVAERIERLIVDGVLKVGQALPSERRLCEKLGISRSALREGLRVLR
GRRIIETSQGRGSFVAELSGNHDASPLMHLFNSQPRTLYDLLEVRALLESESARLAALRG
TDADFVLLRRRYEEMLAAHASEEGADPREHARLDHAFHLAICEASHNPVLVHTLQSLTDL
MLSTVFASVNNLYHRPAQKRQIDRQHSRLYHAVIERLPEQAQRAARDHIHGIRDNLKEIE
QEEQRLVRATMRLEGWT