Protein Info for Psest_0377 in Pseudomonas stutzeri RCH2

Annotation: galactarate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 TIGR03248: galactarate dehydratase" amino acids 16 to 521 (506 residues), 933.9 bits, see alignment E=9.9e-286 PF08666: SAF" amino acids 23 to 92 (70 residues), 28.9 bits, see alignment E=2e-10 PF04295: GD_AH_second" amino acids 123 to 267 (145 residues), 123.1 bits, see alignment E=1.3e-39 PF20629: GD_AH_C" amino acids 277 to 518 (242 residues), 304.5 bits, see alignment E=7.6e-95

Best Hits

KEGG orthology group: K01708, galactarate dehydratase [EC: 4.2.1.42] (inferred from 86% identity to ppw:PputW619_2816)

Predicted SEED Role

"D-galactarate dehydratase (EC 4.2.1.42)" in subsystem D-Galacturonate and D-Glucuronate Utilization or D-galactarate, D-glucarate and D-glycerate catabolism (EC 4.2.1.42)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.42

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GE43 at UniProt or InterPro

Protein Sequence (521 amino acids)

>Psest_0377 galactarate dehydratase (Pseudomonas stutzeri RCH2)
MSETVQLIPHQDSPRCIRLNEADNVAVVVNDGGVPVGAQFEGGLVTVEAVPQSHKVALVD
IGEGEPVRRYGQIIGYALEPIRCGSWVKETQLKMPSAPPLESLPRATAVPDKLAPLDGYT
FEGFRNSDGTVGTRNILGISTTVQCVTGVLEHAVKRIRDELLPKYPNVDDVVALTHSYGC
GVAINARDAYIPIRTVRNLARNPNLGGEALVISLGCEKLQAEQVMHEGDPSVDLREPWLY
RLQESNSGFGEMIEQIMALAETRLKKLDQRRRETVPASELILGMQCGGSDAFSGITANPA
LGYAADLLVRAGATVMFSENTEVRDAVYMLTARAETPEVADALIAEMDWYDRYLERGAAD
RSANTTPGNKKGGLSNIVEKSLGSIVKSGSGAISGVVGPGGRVARKGLIFCATPASDFVC
GTLQLAAGMNLHVFTTGRGTPYGLAMAPVVKVATRTELAERWPDLIDIDAGRIASGRASI
EELGWELFHYYLDVASGRRKTWAEQHRLHNDLVLFNPAPIT