Protein Info for Psest_3821 in Pseudomonas stutzeri RCH2

Annotation: ATP-dependent Zn proteases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 657 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details transmembrane" amino acids 140 to 159 (20 residues), see Phobius details PF07728: AAA_5" amino acids 211 to 283 (73 residues), 23.9 bits, see alignment E=7.5e-09 PF00004: AAA" amino acids 212 to 343 (132 residues), 138 bits, see alignment E=5.4e-44 PF17862: AAA_lid_3" amino acids 366 to 409 (44 residues), 30.3 bits, see alignment 4.8e-11 PF01434: Peptidase_M41" amino acids 427 to 598 (172 residues), 127.4 bits, see alignment E=1.2e-40

Best Hits

KEGG orthology group: K03798, cell division protease FtsH [EC: 3.4.24.-] (inferred from 86% identity to psa:PST_0452)

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GQK4 at UniProt or InterPro

Protein Sequence (657 amino acids)

>Psest_3821 ATP-dependent Zn proteases (Pseudomonas stutzeri RCH2)
MKKPRLIQGRRGLVLSVLSLLLLAAVALWLVQPSAPTDSPAAGSAAAMLGELQSSRESWE
ANRGDLSRLMGDLRGGAIASAALGAEAVYVTTTGEQRYWVPDQSGRVAALLLDQYAVSGA
ELFPLAMFQTDAEKPFYKYLLPYSPIALLLIGAAIFFAMKTRGFDVQRKGSGVTFADVIG
AAEAKQALSDVTAYLRDPAAYARLGARPPKGVLLTGEPGTGKTQLAKALASESNASFIQV
TGSDFSSMYFGVGIQKVKSLFRTARKQAPCIIFIDEIDGIGKRAEQTRSSDAESNRIINQ
FLAEMDGFDGAAGVLVLGATNFPNSLDPALVREGRFDRSIAVGLPGLDDREALFRLYAGK
ITAAADLDFPQLARNTVGLTPAAIAYIVNHAALLAARAGAKQVDMAHFVDAVETCRIGEQ
PSGVTPMSPTDRKRIAVHEAGHALVAAALNVGRVEKVTILPRGQALGVTLVTPVEDKRLH
MYSELRNRIQMLLAGRGAEQLYFHEVSSGAGQDLQEASKIALSMVGALGMGPRGSLLSLQ
AVRDAHLDSDPREALEAADELLQQLNQECLALLQRLKPALDHITERLLAVETVPGEEVLA
AIERLPVQHHEASVSSIIGHALNSIDRVAASAMDSTDSFELSPVVSSEPEDDGPTRL