Protein Info for PGA1_262p01000 in Phaeobacter inhibens DSM 17395

Annotation: dipeptide transport ATP-binding protein DppF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 PF00005: ABC_tran" amino acids 48 to 200 (153 residues), 115 bits, see alignment E=4.1e-37 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 251 to 335 (85 residues), 103.9 bits, see alignment E=1.9e-34 PF08352: oligo_HPY" amino acids 253 to 316 (64 residues), 70.8 bits, see alignment E=1e-23

Best Hits

Swiss-Prot: 52% identical to APPF_BACSU: Oligopeptide transport ATP-binding protein AppF (appF) from Bacillus subtilis (strain 168)

KEGG orthology group: K02032, peptide/nickel transport system ATP-binding protein (inferred from 85% identity to sil:SPO3778)

MetaCyc: 40% identical to murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppD (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]; 7.4.2.6 [EC: 7.4.2.6]

Predicted SEED Role

"Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2B4 at UniProt or InterPro

Protein Sequence (344 amino acids)

>PGA1_262p01000 dipeptide transport ATP-binding protein DppF (Phaeobacter inhibens DSM 17395)
MTTQTQDSKPLLELKNLEKRFELDKGFLETIKLRGGRITREKRAVHAVNNVSLSADRGEA
LCIVGESGCGKSTVARLVAGLLAPSGGEIHYDGERIDDRSRGEMMPLRKKMQMIFQNPYA
SLNPRMTIQQALEEPVRHHNPSLSRGEVRDKVSEVMRSVGVDPSWSSRYPHEFSGGQRQR
IAIARALTVDPEFIIADEPISALDVSIQAQVLNLMLEAKDQRGLTYFFITHDLSVVEHFG
TRVAVLYLGTLCELADTQTLFENPKHPYTKALLSAVPQLKDQGQNHIRLQGEIPTPINLP
QGCPFQTRCAFANARCRESRPRPLRQADGSTVACHAVEENRLNS