Protein Info for HP15_3592 in Marinobacter adhaerens HP15

Annotation: transglutaminase, N-terminal domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 PF08379: Bact_transglu_N" amino acids 6 to 84 (79 residues), 83.9 bits, see alignment 1.6e-27 PF01841: Transglut_core" amino acids 130 to 246 (117 residues), 60 bits, see alignment E=4e-20 PF09899: DUF2126" amino acids 276 to 1097 (822 residues), 1328.2 bits, see alignment E=0

Best Hits

Predicted SEED Role

"Large protein containing transglutaminase-like domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PGP7 at UniProt or InterPro

Protein Sequence (1100 amino acids)

>HP15_3592 transglutaminase, N-terminal domain protein (Marinobacter adhaerens HP15)
MSIHVALSHTTHYCYERPITLGPQIVRLRPCPHARTRILSYSLKVEPEGYFLNWQQDPQA
NYLARLVFPEKTGELKITVDLVAEMAVINPFDFFLEPRAETIPFDYEEWQTAELAPYLQK
LPETPEFRKWMATIDRKETPSVDFLVGVNQSLADRIDYLIRMEPGVQTPEETLKKGSGSC
RDSTWLLVQTLRHLGLAARFVSGYLIQLKADQKALDGPSGAEEDFTDLHAWCEVFLPGAG
WVGLDPTSGLFAGEGHIPLACSPDPSSAAPITGMVEECGVEFEHQMSVQRIWEAPRVTKP
YTEAQWQRIVGLGHDVDQSLTELDVRLTQGGEPTFVANHDRDEPEWNTEAMGPTKRKKAI
ELYHRMRDRYGAGGLVHFGQGKWYPGEPLPRWSLNCYWRKDGEPIWRDERWLADERIEGN
ASPEDAHRFLSALAKELGVDEKQLFPGFEDAFYYLWRERRLPVNVDPFDAKLENALERKQ
LQQIFSRGLDEPVGYVLPLRVSEKEQTWETGPWFLRSERCYLIPGGSPMGHRLPLDSQPW
VEEADYPWIHEQDPFAPRGPLPASEEIRQWNSRGQSGQVSPERAPPKKGKSAPEIVRTAL
CVEPREGILRIFMPPLEKLEPYLALVSAIEKTAKELQQPVLLEGYEPPSDHRLSHFRITP
DPGVIEVNVQPVRTWDELVEQTETLYADAYECRLTSEKFMMDGRHTGTGGGNHFVLGSQK
AEDSPFLRRPDLLRSLISYWHNHPSLSYLFSGLFIGPSSQAPRIDEARNDHVFEMELAFR
EMERLCPVGKKVAPWVVDRLLRDLLTDVTGNTHRAEFCIDKLYSPDGPGGRHGLLELRAF
EMPPHARMSLTQQLLLRALVARFWEQPYKPSGLVRWGTELHDRFLLPHYVWQDFEDVIDD
MKAQGYPLESEWFAPHFEFRFPRIGDYKVKGITLELRSALEPWHVTGEHGAIGGTARYVD
SSLERLQVKVRGAAPDRYQITCNQVPLPLQPTGMVGESVAGVRYRAWQPSQCMHPTIGVD
GPLVFDIVDTWNERSLGGCEYHVTHPGGRNFETLPVNSFEAEGRRMARFFRMGHSSGQQP
LRPVPEHREFPFTLDLRYHK