Protein Info for Psest_3695 in Pseudomonas stutzeri RCH2
Annotation: Histidine ammonia-lyase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 35% identical to HUTH_XANAC: Histidine ammonia-lyase (hutH) from Xanthomonas axonopodis pv. citri (strain 306)
KEGG orthology group: K01745, histidine ammonia-lyase [EC: 4.3.1.3] (inferred from 87% identity to pba:PSEBR_a451)Predicted SEED Role
"Putative histidine ammonia-lyase protein"
MetaCyc Pathways
- L-histidine degradation VI (5/8 steps found)
- L-histidine degradation I (1/4 steps found)
- L-histidine degradation III (2/6 steps found)
- L-histidine degradation II (1/5 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.3.1.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0GQV4 at UniProt or InterPro
Protein Sequence (510 amino acids)
>Psest_3695 Histidine ammonia-lyase (Pseudomonas stutzeri RCH2) MTEPVIFGENLLRIEDVLAVAQRRAPARLQADEAFRSRIARGAQFLDTLLDREGVIYGVT TGYGDSCVVAVPLHQVEALPQHLFTFHGCGLGKLLEAEATRAVLAARLRSLTHGMSGVRI ELLERMQAFLEHDVLPLIPEEGSVGASGDLTPLSYVAAALAGEREVLYRGERRSAAEVHR QLGWTPLTLRPKEALALMNGTAVMTGLACLAYARADYLLQLATRITALNVIALQGNPEHF DERLFAAKPHPGQTQVAAWIRQDLAIDAPAAPLHRLQDRYSIRCAPHVLGVLADSLGLLR QFIETELNSANDNPIIDADNERVLHGGHFYGGHIAFAMDSLKNLVANVADLLDRQLALLV DTRYNHGLPSNLSGAPAATAMINHGFKAVQIGTSAWTAEALKNSMPASVFSRSTECHNQD KVSMGTIAARDALRSLELSEQVAAATLLAAQQGVWLRQRQEDARPLPAPLAAMHSELAET FPPLIEDRALEGELRLCLAQIRNRHWRLYA