Protein Info for PGA1_262p00310 in Phaeobacter inhibens DSM 17395

Annotation: glutathione transport system permease protein GsiC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 102 to 124 (23 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 234 to 256 (23 residues), see Phobius details amino acids 280 to 302 (23 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 4 to 104 (101 residues), 55.9 bits, see alignment E=4.7e-19 PF00528: BPD_transp_1" amino acids 117 to 311 (195 residues), 150.9 bits, see alignment E=3.5e-48

Best Hits

Swiss-Prot: 40% identical to GSIC_ECOL6: Glutathione transport system permease protein GsiC (gsiC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 59% identity to ddr:Deide_3p00580)

MetaCyc: 40% identical to glutathione ABC transporter membrane subunit GsiC (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ESK0 at UniProt or InterPro

Protein Sequence (313 amino acids)

>PGA1_262p00310 glutathione transport system permease protein GsiC (Phaeobacter inhibens DSM 17395)
MATIQYILKRLALMAVTFFLVMIIIFLLVRLLPGDPAIAIAGDRASDADLAAIRERLGLN
QPLVIQFWQFLSNTVQGDLGRSILMRAPVMDVIASRLPTTLFLTTYAVALSVLIAGPLAF
VAALNRGRWPDAVIRTVFQVGLSMPVFYIGLLLLTFLAAQLRWFPVGGYGDSFAERLYHL
FLPSVAVALYTSAIIMRNLRSAIVEVVDAEYVEFARAKGLSAWQILGRHVLRNALISTVT
LLGLSIGNLMSGTLVTETVFAVPGVGRLMLEAIFARDYPLIQGLTLTFAVLVSIVFLLTD
LIQSALDPRMRLT