Protein Info for PGA1_262p00210 in Phaeobacter inhibens DSM 17395

Annotation: alcohol dehydrogenase AlkJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 PF00732: GMC_oxred_N" amino acids 20 to 310 (291 residues), 169 bits, see alignment E=3.5e-53 PF05199: GMC_oxred_C" amino acids 407 to 541 (135 residues), 122.7 bits, see alignment E=4.4e-39

Best Hits

KEGG orthology group: None (inferred from 74% identity to sit:TM1040_0845)

Predicted SEED Role

"Choline dehydrogenase (EC 1.1.99.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.1.99.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.1

Use Curated BLAST to search for 1.1.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ESJ1 at UniProt or InterPro

Protein Sequence (552 amino acids)

>PGA1_262p00210 alcohol dehydrogenase AlkJ (Phaeobacter inhibens DSM 17395)
MLCNDLTTGDMRAVRQVTGFDYIIIGAGSAGCVLADRLSRSGRHKVLILEAGGRGRSPWI
ALPLGYGKTFFDPAVNWKYESVREEALAGRAGYWPRGKGVGGSGAINALVYARGLPQDFD
DWEAAGAIGWGWTSVRQGYEAMETQVAPDGQRRGSGPLHVQDVSDQIHPANRHFFAAAAE
LGLPRTDDINDPGGEGATAYRINTSGGRRMHSARAFLTPALKRKNVTLMTDALVERITFE
GRRAVSVQVRRRGKSMSIAAGREIVLSAGAVASPGLLQKSGIGPAELLRRHGIAIVDDQP
QVGGNLQDHLGINYYFRATEPTLNNVLSPLTGKIRAALHYALWRRGPLALSVNQCGGYFR
SAQSLTRPDQQLYFNPVTYTTTPEGTREVIRPDPFAGFILGFQPSRPTSRGRIDICSADV
SAAPLIRPNSLATEEDRSQVIAGGRLCQRLATTPALDGLIEVAMGTDLRQMADADILSDF
RERCGTVFHPVGTCRMGTDASTSVVCPKLKLHGLDGVRVVDASVFPNITSGNTNAPTMML
AHRAADLILEAT