Protein Info for PGA1_c36300 in Phaeobacter inhibens DSM 17395

Annotation: HTH-type transcriptional regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 201 PF00392: GntR" amino acids 8 to 69 (62 residues), 60.2 bits, see alignment E=1.2e-20 PF07729: FCD" amino acids 79 to 198 (120 residues), 67 bits, see alignment E=2.2e-22

Best Hits

KEGG orthology group: None (inferred from 73% identity to sil:SPO3340)

Predicted SEED Role

"predicted biotin regulatory protein BioR (GntR family)" in subsystem Biotin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DW45 at UniProt or InterPro

Protein Sequence (201 amino acids)

>PGA1_c36300 HTH-type transcriptional regulator, GntR family (Phaeobacter inhibens DSM 17395)
MSVSATISDRIYHALSERIVTGALPAGEKLRQDHIARDFNASHVPVREALLRLEAHGLAQ
SIPRRGMRVTALDPSEIREVIEMRVSLELLALQNAFAHLGSAELEAADAARLACDAATDM
ADWEQKNRAFHRVILSPCGMPRLLATIDDLHIASARHLFANWKHRWSQRVDTDHALIVQA
MRRRDVTTACDILRRHLRRVR