Protein Info for HP15_3469 in Marinobacter adhaerens HP15

Annotation: protein containing DUF876, bacterial

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 TIGR03353: type VI secretion protein, VC_A0114 family" amino acids 5 to 443 (439 residues), 538.1 bits, see alignment E=7.8e-166 PF05936: T6SS_VasE" amino acids 19 to 442 (424 residues), 535.2 bits, see alignment E=5.8e-165

Best Hits

KEGG orthology group: K11893, type VI secretion system protein ImpJ (inferred from 92% identity to maq:Maqu_3726)

Predicted SEED Role

"Uncharacterized protein ImpJ/VasE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PFG2 at UniProt or InterPro

Protein Sequence (444 amino acids)

>HP15_3469 protein containing DUF876, bacterial (Marinobacter adhaerens HP15)
MAVINRVVWSDGLFIKPQHFQQQQRYLEHQINERALAISDYLYGFSDLELNAEYLSFGRV
GLVRASGLFPDGTRFSLPQDDVMPEPLEIADASVANQVVYLALPLGSESLAEVEWPDAPV
AGRFRADSREIRDLHSIDGDAHAIDVGRVAPRLMLEREDRSAYAALAIGRILEKRPDGSL
VMDPNFLPTMLSVRAAPRLQRFVGEMAGLMRERARNIAERVGAPGQGGVADVADFMLLQM
LNRAHPRFMHLARLRQLHPERLFEALLELCGELVTFTDEGRLPREYPAYDHDLPEDAFTP
LMQVLRQSLSTVLEPRALAIQLQQRQYGLTVAPVQDAQLVRDAEFILAVKADMPLDDLRK
QFTQQCKVASVEKIRDLISLQLPGIPLAALPVAPRQLPYHAGFVYFRLDDQSQAWQMLDN
ASGFAFHVAGSFPGMEMQFWAIRS