Protein Info for PGA1_c35210 in Phaeobacter inhibens DSM 17395

Annotation: putative membrane-bound lytic murein transglycosylase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03562: MltA
  • amino acids 101 to 244 (144 residues), 168.8 bits, E=1e-53
• PF06725: 3D
  • amino acids 267 to 337 (71 residues), 84.6 bits, E=4.4e-28

Best Hits

KEGG orthology group: K08304, membrane-bound lytic murein transglycosylase A [EC: 3.2.1.-] (inferred from 75% identity to sil:SPO3885)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

• Ascorbate and aldarate metabolism
• Glycosaminoglycan degradation
• Nucleotide sugars metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

See I7F1N3 at UniProt or InterPro

Protein Sequence (351 amino acids)

>PGA1_c35210 putative membrane-bound lytic murein transglycosylase A (Phaeobacter inhibens DSM 17395)
MMRGLRRALCALALGAGAYLFPQGGQAETSYTMLSFAQLEGWADDDHEAALGAFLQTCRD
LNDPDWRALCALANEQDPKAARGFFQLFFRPVLIEDGAPALFTGYFEPELSGARRPSSRY
RYPVYRQPPESRKISQWLTRRELLTSGVMEGRGLEIAWVDDPVELFFLQIQGSGRIRLPD
GSSIRVGYGGANGHEYRSIGTELVRRGIYNIHQVSAAVIKRWVRRNPLAGEDLLMHNPSY
VFFREVSRIPASAGPLGAMNRSVTTLRSLAVDPRFTPLGAPVWLEKDGAKPMRRLMIAQD
TGSAIKGAQRADVFFGSGDEAGIEAGKLRDPGRMVVLLPIQRAYALLPGDY