Protein Info for HP15_3386 in Marinobacter adhaerens HP15

Annotation: phosphate ABC transporter, ATPase subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 TIGR00972: phosphate ABC transporter, ATP-binding protein" amino acids 45 to 292 (248 residues), 399.6 bits, see alignment E=2.3e-124 PF00005: ABC_tran" amino acids 61 to 216 (156 residues), 109.2 bits, see alignment E=2.6e-35

Best Hits

Swiss-Prot: 83% identical to PSTB_ALCBS: Phosphate import ATP-binding protein PstB (pstB) from Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)

KEGG orthology group: K02036, phosphate transport system ATP-binding protein [EC: 3.6.3.27] (inferred from 90% identity to maq:Maqu_3626)

MetaCyc: 55% identical to phosphate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-27-RXN [EC: 7.3.2.1]; 7.3.2.1 [EC: 7.3.2.1]

Predicted SEED Role

"Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (TC 3.A.1.7.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.27 or 7.3.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRQ3 at UniProt or InterPro

Protein Sequence (292 amino acids)

>HP15_3386 phosphate ABC transporter, ATPase subunit (Marinobacter adhaerens HP15)
MNTTITSEVTQPDEVAVPVQESKPAETIIEEGKTVGKPYSDDPKFKLRDVEVFYGDAPAI
KKISLDIGRNEVIAFIGPSGCGKSTFLRCLNRMNDSIDICRVKGSLQLDDHDIYDPKRDV
VELRARVGMVFQKPNPFPKSIYDNVAYGPRIHGLANRKSDLDEIVENSLRKAGLWEEVKD
RLDANATGMSGGQQQRLCIARAIAVSPEVVLMDEPCSALDPIATAKVEELIAELSESYTI
VIVTHSMQQAARVSHRTAYFHLGHLVEVNETNKVFTSPEHELTESYITGRFG