Protein Info for Psest_3464 in Pseudomonas stutzeri RCH2

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 130 to 154 (25 residues), see Phobius details PF00672: HAMP" amino acids 152 to 206 (55 residues), 22.3 bits, see alignment 2.1e-08 PF00512: HisKA" amino acids 212 to 274 (63 residues), 58.8 bits, see alignment E=6.7e-20 PF02518: HATPase_c" amino acids 323 to 421 (99 residues), 67.8 bits, see alignment E=1.6e-22

Best Hits

KEGG orthology group: None (inferred from 73% identity to psa:PST_0914)

Predicted SEED Role

"two-component system sensor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GMG8 at UniProt or InterPro

Protein Sequence (425 amino acids)

>Psest_3464 Signal transduction histidine kinase (Pseudomonas stutzeri RCH2)
MLAKQPFARRIVIAFTLMTLVVSGTFSLGIVAVVHFIEEHLVTQELGRELDSVLNDVMVH
GDAPRLDAATRFFASNLPGYAIPEAFRGLGDGFTELVRNDDAYYVYQREIDGAKYLLVEE
QHEFEARENALFMVVLAGFLLSIVGAWGLGWLMARKVMAPLSRLAQQVRHRDQLHPMAPP
LALQYPDDEVGHVAAAFDSTLGQLRQTLERERLFTADVSHELRTPLMVVLGACELLEQQA
ELPPAAQRPLARIQRAAQEMHELVETFLMLARARPQQTSLAGDTSLRSVATEQSERWAPL
LAEKGLAFELREEGEDKGVYNHTLLATVMSNLLRNALHYTDRGTVRLVLSEGGFRVEDSG
VGIPLAEQERMFQPFVRGAEGRGEGLGLGLSLVKRICAHQSWQVGVVPRQPQGSCFQVRF
DDGVV