Protein Info for PGA1_c34500 in Phaeobacter inhibens DSM 17395

Annotation: 3'(2'),5'-bisphosphate nucleotidase CysQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 PF00459: Inositol_P" amino acids 5 to 248 (244 residues), 172.9 bits, see alignment E=4.9e-55 TIGR01331: 3'(2'),5'-bisphosphate nucleotidase" amino acids 10 to 255 (246 residues), 264.3 bits, see alignment E=5.8e-83

Best Hits

KEGG orthology group: K03677, CysQ protein (inferred from 82% identity to sil:SPO0039)

Predicted SEED Role

"3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7)" (EC 3.1.3.7)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DVJ1 at UniProt or InterPro

Protein Sequence (265 amino acids)

>PGA1_c34500 3'(2'),5'-bisphosphate nucleotidase CysQ (Phaeobacter inhibens DSM 17395)
MTYDDLIPVIRRLAIEAGEKIMEIYNSDEFEVKVKSDESPVTAADEAADALISAGLRAAF
PDVMLVTEEQADSHSKSGDTFLIVDPLDGTKEFIHRRGDFTVNIALVEKGVPTRGVVYAP
ARSRMFFTLADGSAVEETGAFDPAAMGEIKPIRVADSNNDALMVVASKSHRDQATDDYIN
KYAVKDSKSAGSSLKFCLVATGEADLYPRVGRTMEWDTAAGHAVLGGAGGQVVRFDDHAP
LTYGKEGYANPFFIAYAPGVELKKA