Protein Info for HP15_3276 in Marinobacter adhaerens HP15

Annotation: membrane protein containing DUF423

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 119 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 36 to 55 (20 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details amino acids 91 to 112 (22 residues), see Phobius details PF04241: DUF423" amino acids 13 to 100 (88 residues), 111.6 bits, see alignment E=8.6e-37

Best Hits

Swiss-Prot: 50% identical to Y588_STAAR: UPF0382 membrane protein SAR0588 (SAR0588) from Staphylococcus aureus (strain MRSA252)

KEGG orthology group: None (inferred from 68% identity to maq:Maqu_3505)

Predicted SEED Role

"COG2363"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PQY3 at UniProt or InterPro

Protein Sequence (119 amino acids)

>HP15_3276 membrane protein containing DUF423 (Marinobacter adhaerens HP15)
MAGAFLALVAVMAGAFGAHGLRNLVSERGLEVFETAVTYQMYHSIALVLLALLAAQGLSR
KLLAWSAGFFLAGILLFSGSLYLLVLTDIRWIGPITPLGGLCFMVGWALLITSGLRRNK