Protein Info for PGA1_c33750 in Phaeobacter inhibens DSM 17395

Annotation: putative glycine betaine transport system substrate binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF04069: OpuAC" amino acids 26 to 309 (284 residues), 158 bits, see alignment E=1.8e-50

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 82% identity to dsh:Dshi_1438)

Predicted SEED Role

"L-proline glycine betaine binding ABC transporter protein proX (TC 3.A.1.12.1) / Osmotic adaptation" (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ERM6 at UniProt or InterPro

Protein Sequence (321 amino acids)

>PGA1_c33750 putative glycine betaine transport system substrate binding protein (Phaeobacter inhibens DSM 17395)
MKTKLKSLGFAATVSIFAMPALAGEEVKIGVPSWTGAQAIAHLLGAVVEMRIGGKVEFVP
GNNATIFQAMDQGKGDIDVHPDVWLPNQQSFTQKYVDEAGTVTLSSNPYEGNQGFCVSQD
FGEANNVTDIADLGRPDVAALMDSDGNGKGELWIGAPGWASANVNEVKTRDYGLLDFIDP
VRAEESVKTARIKDSIAKGEGYAFYCYKPHAVWYMFDVRMLSEPTFDPEKYTMVQPSDDP
DWYDKSSVATKDALKNVQIAWSNSLEGRSPAIAEFFANFALTADDVSGFAYEISGKGREP
ADVAREWVEANPDRVDAWLGL