Protein Info for HP15_329 in Marinobacter adhaerens HP15

Annotation: two-component sensor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 987 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 39 to 59 (21 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 114 to 137 (24 residues), see Phobius details amino acids 152 to 171 (20 residues), see Phobius details amino acids 183 to 210 (28 residues), see Phobius details amino acids 238 to 257 (20 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details amino acids 323 to 349 (27 residues), see Phobius details amino acids 370 to 390 (21 residues), see Phobius details amino acids 397 to 420 (24 residues), see Phobius details amino acids 427 to 448 (22 residues), see Phobius details amino acids 468 to 489 (22 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 628 to 743 (116 residues), 39.3 bits, see alignment E=3.1e-14 PF00989: PAS" amino acids 629 to 710 (82 residues), 35.2 bits, see alignment E=1.6e-12 PF00512: HisKA" amino acids 753 to 813 (61 residues), 41.5 bits, see alignment 1.6e-14 PF02518: HATPase_c" amino acids 861 to 971 (111 residues), 88.1 bits, see alignment E=8.1e-29

Best Hits

KEGG orthology group: None (inferred from 85% identity to maq:Maqu_0671)

Predicted SEED Role

"Two-component sensor CbrA: intrcellular carbon:nitrogen balance"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PL51 at UniProt or InterPro

Protein Sequence (987 amino acids)

>HP15_329 two-component sensor (Marinobacter adhaerens HP15)
MSFSPSGLLLASLLYLILLFGIAWFTEKGMVPRRWVRHPLVYVLSLGVYAGIWAVYGAVG
MAAESGYGFLAYYLGISGAFLLAPVLLNPVMRIGRAYQLTSLADLFAYRYRSQWAGTLVT
LCSGGAILALLSMQIQAVATSASILAPDTSPAVISVMFSLIVVLFAMLFGARRDQNSENH
QGLVLAIAFDSLVKLVALLVLGGVILFGVFDGMSGLESWLDNRTSPATTMTLSIDDGSWR
ALMLMSFAAALVLPHMYHMTFSENPSPKALAKASWGLPLYLLLLGLPVPLILWGGQELAV
TTGPGFFAIGAAQAMESPALTLLMYIAGLSAASGLMIVSTLALAGMALNHVVLPLKTPKD
QGDIYRWLQWIKRLLIAVIIFLALLFHEVVGKNLDLSILGAISLSGTLQLLPGALGVIYW
PEGNRRGLIAGLVVGLAIWVVTLVLPFSHTANLLAWLDAPLIPDYSNWHIFTFVSLTANI
TVFALISILSTSTSEENSAAQACSLGALSRPQRRELLATSSSDFVRQLAEPLGYGVARRE
VERALGQLKLPNVEYRPYQLRRLRDQVEINLSGLLGPSVARDMVKRHLGFKPMAQGGTAQ
DIRYVERALGDYQNRLTGLAGELDNLRRHYRQTLQNLPIPACSVGEDGEILMWNHAMEAL
TGITADDVVGARLMALPEHWHLLLDDFNRGPDLHRYKHRLDLRGKPHWLNLHKAALSGPD
HTEGGSIILVEDQTETRLLEDELMHSERLASVGRLAAGVAHEIGNPVTGISSLAQNLKLE
TDNPDILDTADQIQQQTRRISTILQSLMNFARTGNHAQANRYEPVAIHRCVEESINLLSL
SDKGLGIHYVNDCPPSLQVLGDEQRLVQVFVNLLANARDASPEGGTIRVSGKGDGYSAII
EVVDEGSGIPGDQLDHIFEPFYTTKAPNKGTGLGLSLVYSIIEEHYGNVQVESPANADTG
RGTCVRLRLPAYEPETGTIAISQNQRS