Protein Info for HP15_3250 in Marinobacter adhaerens HP15

Annotation: cyclopropane-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 PF02353: CMAS" amino acids 148 to 410 (263 residues), 294.7 bits, see alignment E=2.7e-91 PF08704: GCD14" amino acids 196 to 263 (68 residues), 27.5 bits, see alignment E=1e-09 PF13489: Methyltransf_23" amino acids 202 to 319 (118 residues), 42.7 bits, see alignment E=2e-14 PF13847: Methyltransf_31" amino acids 204 to 311 (108 residues), 37.2 bits, see alignment E=9.7e-13 PF05175: MTS" amino acids 204 to 298 (95 residues), 24.5 bits, see alignment E=7.4e-09 PF13649: Methyltransf_25" amino acids 209 to 303 (95 residues), 56.2 bits, see alignment E=1.9e-18 PF08242: Methyltransf_12" amino acids 210 to 304 (95 residues), 42.7 bits, see alignment E=3.2e-14 PF08241: Methyltransf_11" amino acids 211 to 306 (96 residues), 51.1 bits, see alignment E=7e-17

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 82% identity to maq:Maqu_3480)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PQV7 at UniProt or InterPro

Protein Sequence (437 amino acids)

>HP15_3250 cyclopropane-fatty-acyl-phospholipid synthase (Marinobacter adhaerens HP15)
MNQSTAQKTRDNGQESKSHVLTLPLENTHVDRSPHTYERWLIAKLMRMAGSPPLRFRLWN
GDVIEPEGQHAQFTLHLTDPKALYALVTNPNLAFGDLYSAGRLEVEGDLPDLMETLYRSV
HQARQKWPKWLEALWRNHNPRSTGIPEAKENIHHHYDLGNEFYQLWLDSAEMQYTCAYYE
TPDLSLEQAQLAKLEHVCRKLRLKPGMTVVEAGCGWGGLARYMARNYGVKVHSYNISREQ
LAFAREEARKQELDHLVEYIEDDYRNISGQYDAFVSIGMLEHVGKENYEALSELIKRSLK
PDGIALLHSIGRNRPMLMNAWIEKRIFPGAYPPSIGEFMQICEHGDFSVLDVENLRLHYA
QTLSHWMERFNQNEDKVTAMYDGHFTRAWRMYLAGSIAAFRAGSLQLFQVVFSHGDNNQL
PRNRRDLYDFPAAAEEA