Protein Info for PGA1_c33280 in Phaeobacter inhibens DSM 17395

Annotation: putative LL-diaminopimelate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00155: Aminotran_1_2
  • amino acids 30 to 385 (356 residues), 138.7 bits, E=2.9e-44
• PF12897: Asp_aminotransf
  • amino acids 171 to 391 (221 residues), 31.1 bits, E=1.2e-11

Best Hits

KEGG orthology group: None (inferred from 79% identity to sit:TM1040_0059)

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.6.1.17)

MetaCyc Pathways

• aspartate superpathway (23/25 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
• L-lysine biosynthesis I (9/9 steps found)

KEGG Metabolic Maps

• Lysine biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.17

Use Curated BLAST to search for 2.6.1.17

Sequence Analysis Tools

See I7ERJ4 at UniProt or InterPro

Protein Sequence (392 amino acids)

>PGA1_c33280 putative LL-diaminopimelate aminotransferase (Phaeobacter inhibens DSM 17395)
MNFPERFSNLPPYAFPRLRALLDHHTPGGDVVHMTIGEPKHDFPAWVTDVIVDNAAGFQS
YPPNEGSAELRGAISDWIKRRYDVSVDPMTQVMALNGTREGLYNAAMALCPEQKNGAKPV
VLIPNPFYQVYMVASISVAAEPVFVPATADTDHLPDYVGLPPEVLNRTAVAYICSPANPQ
GAVASRAYWTQLIQLAEQYDFRIFADECYSEIYRASAPVGALSVAQELGADPERVVLFNS
LSKRSNLAGLRSGLIAGGPDTMKRVHQLRAYSGAPLPAPLQAAAARVWADEAHVTENRAL
YQEKYRIADQVFDGLDGYMAPEAGFFLWLPVEDGEAAALKLWQDTGVRVLPGAYLAQGDG
TANPGKGYIRVALVAPAEQTEVALRTLRSCLY