Protein Info for HP15_3177 in Marinobacter adhaerens HP15

Annotation: conserved hypothetical protein, secreted

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 59% identity to hch:HCH_02944)

Predicted SEED Role

"Zinc-regulated TonB-dependent outer membrane receptor" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PQ76 at UniProt or InterPro

Protein Sequence (373 amino acids)

>HP15_3177 conserved hypothetical protein, secreted (Marinobacter adhaerens HP15)
MFKRFAPFAILPLAMTAGGATANELNPDVSVTLDGYYKQNETALSHREQGFGLGHTELSL
SSPIDDLFSGRLTAVFEEHDGESEVLIEEAYLQTNGLPYALNVRAGRFLSQVGYLNGRHM
HEDDFVERPAAYRAMLGSHYYDTGARLNVLLPTPFFWQVGAEAFAGDQLTEGDEDIGVYT
VNTRLGGDISLSQSWQLGLSWLRNRHAKSADTGDGSHDHDHEEGHDHGHSHGAGYTSENL
YIADVVWKWAPNGNNREQQLTLSGEYLYGDELNQFAASDDTNEGWYVSGVYQFAPQWSAG
VRYGEVDLQEAHGDHFHNQTLEETDVMLSWSRSHFSTVRLQYTHQEATGFSNADNTVMVQ
YIMSLGAHGAHGY