Protein Info for PGA1_c32480 in Phaeobacter inhibens DSM 17395

Annotation: N-formylglutamate amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 PF05013: FGase" amino acids 17 to 248 (232 residues), 253.1 bits, see alignment E=1.7e-79

Best Hits

KEGG orthology group: None (inferred from 65% identity to sil:SPO3282)

Predicted SEED Role

"N-formylglutamate deformylase (EC 3.5.1.68)" in subsystem Histidine Degradation (EC 3.5.1.68)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.68

Use Curated BLAST to search for 3.5.1.68

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F0Y3 at UniProt or InterPro

Protein Sequence (286 amino acids)

>PGA1_c32480 N-formylglutamate amidohydrolase (Phaeobacter inhibens DSM 17395)
MSDTVYLVEMPQELRSGVVFASPHSGSDYSAAFLAQTILDPLQLRSSEDAFVDELFAAAP
RFGMPLLTARAPRAYVDLNRSTEELDPALIEGVIKRGQNPRVASGLGVVPRVVAHGRAIY
HGKLSQCEARRRIESYWRPYHAALQQLLDQARIGFGQAVLIDCHSMPHEAISAAGRRGAG
LPDVVLGDRFGAAASSEVMDRVEAAFVGAGLRVARNTPFAGAYITQTYGRPSRAQHAVQV
EIDRSLYMNEARIEKTADFAALQMVLTDVIAELSQLNCDPVPLAAE