Protein Info for PGA1_c32100 in Phaeobacter inhibens DSM 17395

Annotation: glutathione import ATP-binding protein GsiA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 535 PF00005: ABC_tran" amino acids 19 to 177 (159 residues), 101.6 bits, see alignment E=2e-32 amino acids 299 to 448 (150 residues), 114.8 bits, see alignment E=1.7e-36 PF08352: oligo_HPY" amino acids 228 to 251 (24 residues), 19 bits, see alignment (E = 5.5e-07) amino acids 500 to 527 (28 residues), 27.1 bits, see alignment (E = 1.6e-09)

Best Hits

KEGG orthology group: K02031, peptide/nickel transport system ATP-binding protein K02032, peptide/nickel transport system ATP-binding protein (inferred from 71% identity to sil:SPO0098)

Predicted SEED Role

"Peptide/opine/nickel uptake family ABC transporter, ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F0V8 at UniProt or InterPro

Protein Sequence (535 amino acids)

>PGA1_c32100 glutathione import ATP-binding protein GsiA (Phaeobacter inhibens DSM 17395)
MTLLEITNLSLSIGAFPILRDVSLSVDPGEILAITGESGSGKSLTALTILRLLPNCTRLS
GHLSLEGQDLLSLSEEQMCDLRGRKIGMVFQEPMTALNPVQSIGDQVMETLLLHSSATKA
EAEAEARSLLDRVGLPAERFPLSRYPHELSGGQRQRVVIAMAIAMRPALLIADEPTTALD
VTTQAQILDLLRDLVRDYGMGMIIITHDLAVVADMADRIIVMRKGEVVETGSTAQLLANR
RHPYTQKLFAASNHQADLPTAKTTDPQDTPLLEVRNAVRDYPLPRKRLFAPAEQMRAVDH
VSFALHRGERLGLVGESGCGKSTLTRAILGLEPLQGGEILLDGTPLSGKGLTAEQRRKMQ
VVFQDPFGSFNPRHRVARLITEPFHGVPDAPTGQERDDRVAEALSAVGLSPNDAGRYIHQ
FSGGQRQRIAIARALITRPDLILFDEAVSALDVSVRAQILDLLAELCSAYGLSYLFISHD
LHVVRSMTDRCLVMQKGQIVEYGKTEDLFADPQHPYTTSLIAAAPVLPDLATGAA