Protein Info for PGA1_c32070 in Phaeobacter inhibens DSM 17395

Annotation: Deacetylases, including yeast histone deacetylase and acetoin utilization protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 PF00850: Hist_deacetyl" amino acids 43 to 328 (286 residues), 230.6 bits, see alignment E=1.4e-72

Best Hits

KEGG orthology group: K04768, acetoin utilization protein AcuC (inferred from 72% identity to rde:RD1_0096)

Predicted SEED Role

"Deacetylases, including yeast histone deacetylase and acetoin utilization protein" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E4Y3 at UniProt or InterPro

Protein Sequence (394 amino acids)

>PGA1_c32070 Deacetylases, including yeast histone deacetylase and acetoin utilization protein (Phaeobacter inhibens DSM 17395)
MTQFTAAPTRPATADTATLFGPLEAPLFIGSEIYRGSSYGRMHPLRVPRVSTVMDLTRAL
GWLPAAQYQTSPRAKPAALERWHSPEYIAALQAAERAQAVSEEVKARHHIGTISNPVFPE
IFRRPATAAGGSILAGERLAQGGVIYNPAGGTHHGMPDRANGFCYLNDPVLAMLSLRHHG
AKRIAYVDIDAHHADGVEHGFAGDPDVLMISTHEENLWPKTGKLVDDAGGSALNLPVPRG
FNDSEMAYVLEELILPAVVNFAPDAVVLQCGADAVTEDPLAHLDLSNTAHWSVVAALRSL
APRYLVLGGGGYNPWSVGRLWTGVWAVLNGHEIPDRLPPAAEGVLRGLEFKGHRLGRNPP
EHWFTTLRDDPRPGPVREQIREAVTLLRRRRGLR