Protein Info for PGA1_c31970 in Phaeobacter inhibens DSM 17395

Annotation: peptidyl-tRNA hydrolase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 139 PF00472: RF-1" amino acids 7 to 133 (127 residues), 76.7 bits, see alignment E=7.2e-26

Best Hits

Swiss-Prot: 49% identical to ARFB_PSEPU: Peptidyl-tRNA hydrolase ArfB (arfB) from Pseudomonas putida

KEGG orthology group: K15034, ribosome-associated protein (inferred from 78% identity to sit:TM1040_2666)

Predicted SEED Role

"Hypothetical protein YaeJ with similarity to translation release factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E4X6 at UniProt or InterPro

Protein Sequence (139 amino acids)

>PGA1_c31970 peptidyl-tRNA hydrolase-like protein (Phaeobacter inhibens DSM 17395)
MLRITDTIALQDWELTESFMRASGPGGQNVNKVSSAVELRFEAARSPALTPAVKSRLKRL
AGRRWTKDGAIILQCDETRSQQRNRDLVRERLAELIRQALVVPKRRIATKPTRGSVRRRL
DAKRQRSDVKATRGKIDPD