Protein Info for HP15_3058 in Marinobacter adhaerens HP15

Annotation: leucine/isoleucine/valine transporter ATP-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 PF00005: ABC_tran" amino acids 18 to 178 (161 residues), 121.9 bits, see alignment E=4.7e-39 PF12399: BCA_ABC_TP_C" amino acids 227 to 251 (25 residues), 40.4 bits, see alignment (E = 2.6e-14)

Best Hits

Swiss-Prot: 68% identical to LIVG_SALTI: High-affinity branched-chain amino acid transport ATP-binding protein LivG (livG) from Salmonella typhi

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein (inferred from 93% identity to maq:Maqu_3338)

MetaCyc: 67% identical to branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (Escherichia coli K-12 substr. MG1655)
ABC-15-RXN [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PNZ2 at UniProt or InterPro

Protein Sequence (251 amino acids)

>HP15_3058 leucine/isoleucine/valine transporter ATP-binding subunit (Marinobacter adhaerens HP15)
MLEVQNLSMRFGGLLAVDEVSLDVQEHEIVSIIGPNGAGKTTVFNCMSGFYKPTGGKILF
EGKEVQGKPDYKISRLGMVRTFQHVRLFSQMTVVENLLVAQHRHLNTNLISGLIQTPSYR
KKEQKSLDRAAYWLDRVGLLDMANREAGNLAYGQQRRLEIARCMVTEPKLLMLDEPAAGL
NPAETKELNQLIISLKEDYNVSVVLIEHDMSLVMDISDRINVINQGRPLASGTPEEIRQN
DDVIKAYLGEA