Protein Info for PGA1_c31530 in Phaeobacter inhibens DSM 17395

Annotation: putative cytosol aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 PF21337: Peptidase_M17_N_1" amino acids 18 to 137 (120 residues), 69.2 bits, see alignment E=3.5e-23 PF00883: Peptidase_M17" amino acids 154 to 445 (292 residues), 343.8 bits, see alignment E=1e-106

Best Hits

KEGG orthology group: K01255, leucyl aminopeptidase [EC: 3.4.11.1] (inferred from 66% identity to sil:SPO3717)

Predicted SEED Role

"Peptidase B (EC 3.4.11.23)" (EC 3.4.11.23)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.1

Use Curated BLAST to search for 3.4.11.1 or 3.4.11.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F348 at UniProt or InterPro

Protein Sequence (464 amino acids)

>PGA1_c31530 putative cytosol aminopeptidase (Phaeobacter inhibens DSM 17395)
MPSAKHPAFAKPDTASIALHVLDQDSCEGWLAKAPAETATWARANGFNGAVGQILTLPDK
DGHPRQALVGYGTEKDRARRRFILAGAVSKLPKGTYHLVEGIAQQDRSAECLGWLLAQYQ
FDRYKKGRDTETHLIAPEDIDGARIEALAAGEFLTRDLINTPAADMGPAELQDAAQALAD
QHGASLDVIADQDLLTQNFPMIHTVGRASDRRPRLLEMRWGSTGPKLTLVGKGVCFDTGG
LNLKPGSSMGLMKKDMGGAANVMGLAHMIMALKLPVELRVLIPAVENSVSANAFRPGDVL
TARNGLTVEINNTDAEGRLVLADALAYAAEDTPDLLISMATLTGAARVAVGPDLAPFYTD
DDADADAVGTAAAAVADPVWRMPFHAPYEAMIEPQIADLDNAPSGGFAGSITAALFLRRF
AGEHRYMHFDIYGWTPSAAPARPKGGALQGARAVFEALPQMLKL