Protein Info for PGA1_c30690 in Phaeobacter inhibens DSM 17395

Annotation: putative type I restriction-modification system, R subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1088 TIGR00348: type I site-specific deoxyribonuclease, HsdR family" amino acids 7 to 768 (762 residues), 409.9 bits, see alignment E=1.1e-126 PF04313: HSDR_N" amino acids 7 to 224 (218 residues), 120.9 bits, see alignment E=1.3e-38 PF04851: ResIII" amino acids 298 to 474 (177 residues), 73.3 bits, see alignment E=4.5e-24 PF18766: SWI2_SNF2" amino acids 301 to 539 (239 residues), 240.5 bits, see alignment E=3.5e-75 PF22679: T1R_D3-like" amino acids 675 to 749 (75 residues), 49.8 bits, see alignment 1.1e-16

Best Hits

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2T9 at UniProt or InterPro

Protein Sequence (1088 amino acids)

>PGA1_c30690 putative type I restriction-modification system, R subunit (Phaeobacter inhibens DSM 17395)
MGHEFDDVEQPFIDQCVAMGWQAQTGNMDDPALTGRTSFKQVIAEATLRERLRAINPGPD
GKPWLDEARLSEAVSALTRHGQRGLMEANQAVTELLLKGLTVEGLPEWDGGRGQTIRYIA
WDDVAANSFTVSNQFRVDCPPGHDVGKGFIIPDVVMLVNGIPMVVVEAKSPGIPEPLAEA
VKQLRRYHNARKAALEVDENEGAPALFASVQLLIATSFDEARVGCIGAGLEYYGQWKTVV
GPDGKGSEDEVAKALGKTRLSEQERMIAGMLRPAHLLDILRHYLLFMNVGGQTIKTVCRY
QQYRAVNRALERLRTGKTRVQDGEYDRRGGIVWHTQGSGKSLTMVFMIRKMRTDLDLRKF
KVIMVTDRKDLQRQLSETATMSGDVVELAISNSSLKRLARRKGPGLVFATIQKYRTDEDV
AEVTKGPAFDVLNEDDTILVVVDEAHRTQAGDLHANLLAALPNCARIGFTGTPIIMGEKK
RSTEIFGDFIDQYTIKEAEADGATVPVLYEGRTAEGAVKDGATLDGLFEDMFRGRSDEEL
EAIRKKYATKGNILEAKELIGEKARDMLRHYVTNLLPNGYKAQVVAYSRTAVVRYHAAFL
EARDELLAEAAALPDCDKSLDDEELCIRPAKLQALVQAWRYRDTLEKIEFAAIMSGGNND
DASWKQWTESSAQEMRIKRFKKPLFHNDSTKADPLAFLIVKSMLLTGFDAPIEGVMYLDR
SIREAELLQAIARVNRTGFGKTCGIVVDYFGVAHHLKSALSAYSDEDIDGALVSLTDQIP
ILRDRHIRVVDIFRREGLDDLSDDEKCLQVLATEKVRAEFTVKLKDFLKSLEIVLPRPEG
LPFVKDAKRLAYIQTRARNRFRDVAVIGSDVGAKVRKLIDDHVISLGIDPKIPPVQLTDA
EFEDQVGQASGARAKASEMEHAIRSHIRKKLETDPVRFKKMSERLNQILDGFGHQWDEII
EQLQAIIDELRSESQSTGETEFDIPEIYVPFLRTVLEEAGADENTPAQHLQALHRVTQEI
VDRIVDEVVANRSIWSTFKMADQENLRSEIFEKLVDAKIEGLGVLDAERLSEQLMQQAKA
NDEALRGF