Protein Info for HP15_2925 in Marinobacter adhaerens HP15

Annotation: adenosylmethionine-8-amino-7-oxononanoate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 TIGR00508: adenosylmethionine-8-amino-7-oxononanoate transaminase" amino acids 14 to 443 (430 residues), 569.5 bits, see alignment E=1.7e-175 PF00202: Aminotran_3" amino acids 27 to 437 (411 residues), 347.5 bits, see alignment E=4.6e-108

Best Hits

KEGG orthology group: K00833, adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC: 2.6.1.62] (inferred from 92% identity to maq:Maqu_3049)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PN56 at UniProt or InterPro

Protein Sequence (450 amino acids)

>HP15_2925 adenosylmethionine-8-amino-7-oxononanoate transaminase (Marinobacter adhaerens HP15)
MRNADLVTRGLKSVWHPCTQMKDHEGAVPLVPIKRGEGVWLEDFEGNRFIDAVSSWWVNL
FGHANPRINAAIQKQIGELEHVILAGFTHEPVVNLSERLIEVTPPGLNKVFYADNGSSAI
EAALKMSFHYWKNHDKPGKKNFVNLSNSYHGETLGALALGDVSLYKDTYQPLLMEVLTAP
SPDAFNKEPGETDEDYALRQFEAMEKLLAEKHEEICAVVVEPLIQCAGGMRMHHPIYHTK
LREACDRYGVHLIADEIAVGFGRTGTLFACEQSGITPDFMCLSKGLTAGYLPLSVVLTTD
DVYNAFYDDYETLKAFLHSHSYTGNPIGCAVALATLDIFRDDNVIESNRALSTCMAESVA
HLADHPNVGDIRQHGMTLAVEMVKDKASKTPFPWQERRGIRVYQHALTRQALLRPLGNVV
YFMPPYVITEEQIRHLAQVATEGIEIAVRD