Protein Info for PGA1_c30140 in Phaeobacter inhibens DSM 17395

Annotation: transcriptional activator protein FnrL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF00027: cNMP_binding" amino acids 40 to 123 (84 residues), 49 bits, see alignment E=7.4e-17 PF13545: HTH_Crp_2" amino acids 156 to 233 (78 residues), 61.7 bits, see alignment E=7.7e-21 PF00325: Crp" amino acids 185 to 216 (32 residues), 43.2 bits, see alignment 3.7e-15

Best Hits

Swiss-Prot: 78% identical to FNRL_RHOS4: Transcriptional activator protein FnrL (fnrL) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: K01420, CRP/FNR family transcriptional regulator, anaerobic regulatory protein (inferred from 81% identity to sil:SPO3531)

Predicted SEED Role

"Fnr-type transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E4F5 at UniProt or InterPro

Protein Sequence (246 amino acids)

>PGA1_c30140 transcriptional activator protein FnrL (Phaeobacter inhibens DSM 17395)
MNAPTIQNVNCGDCPIRHRAVCARCDADELDVLDSIKYYRTYDAGQPITWSGDRMDFVGS
VVSGIATLTQTMEDGRTQMVGLLLPSDFVGRPGRDTAAYNVVATSTVVMCCFRKKPFEEM
MAKTPHVAHRLLEMTLDELDAAREWMLVLGRKTAREKIASLLSILARRDASLQLHKDSNR
RVFDLPLTREAMADYLGLTLETVSRQVSALRKDGVIELEGKRHVIVPDMGRLMDEAGDDS
DGGYLI