Protein Info for HP15_2885 in Marinobacter adhaerens HP15

Annotation: secreted protein containing competence protein ComEA, helix-hairpin-helix region domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 89 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR00426: competence protein ComEA helix-hairpin-helix repeat region" amino acids 26 to 88 (63 residues), 80.1 bits, see alignment E=5e-27 PF12836: HHH_3" amino acids 27 to 87 (61 residues), 75.6 bits, see alignment E=5.7e-25 PF03934: T2SSK" amino acids 28 to 88 (61 residues), 30.8 bits, see alignment E=6.3e-11 PF00633: HHH" amino acids 29 to 55 (27 residues), 27.3 bits, see alignment E=4.5e-10

Best Hits

KEGG orthology group: K02237, competence protein ComEA (inferred from 65% identity to maq:Maqu_3003)

Predicted SEED Role

"Competence protein ComEA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PMD7 at UniProt or InterPro

Protein Sequence (89 amino acids)

>HP15_2885 secreted protein containing competence protein ComEA, helix-hairpin-helix region domain (Marinobacter adhaerens HP15)
MKRTPLFATLILLFSLVTGFAYAQDAAININTADVATLASLNGIGQSKAEAIVAYREANG
PFAVTADLANVKGIGERTIEKNAARLTVK