Protein Info for PGA1_c29450 in Phaeobacter inhibens DSM 17395

Annotation: SsrA-binding protein SmpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 158 TIGR00086: SsrA-binding protein" amino acids 12 to 155 (144 residues), 179.1 bits, see alignment E=2.5e-57 PF01668: SmpB" amino acids 13 to 155 (143 residues), 188.7 bits, see alignment E=2.6e-60

Best Hits

Swiss-Prot: 89% identical to SSRP_RUEST: SsrA-binding protein (smpB) from Ruegeria sp. (strain TM1040)

KEGG orthology group: K03664, SsrA-binding protein (inferred from 89% identity to sit:TM1040_2482)

Predicted SEED Role

"tmRNA-binding protein SmpB" in subsystem Heat shock dnaK gene cluster extended or Staphylococcal pathogenicity islands SaPI or Trans-translation by stalled ribosomes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DU43 at UniProt or InterPro

Protein Sequence (158 amino acids)

>PGA1_c29450 SsrA-binding protein SmpB (Phaeobacter inhibens DSM 17395)
MAKQKSDPNYKVIAENRRARFDYAIEDDLECGILLEGSEVKSLRVGGTNIAESYATVDDG
ELWLVNSYIAPYEQAKMFRHEERRRRKLLVSRKELSNLWNATQRKGMTLVPLVMYFNHRG
LAKIKIGIAKGKKNHDKRETEAKRDWSRQKQRLLKDHS